Steffen Lindert

15 papers Journal 15
YearRankTypeTitle / Venue / Authors
2024 J jnl
Discovery of Nanomolar Inhibitors for Human Dihydroorotate Dehydrogenase Using Structure-Based Drug Discovery Methods.
J. Chem. Inf. Model.
William T. Higgins, Sandip Vibhute, Chad Bennett, Steffen Lindert
2023 J jnl
Predicting ion mobility collision cross sections using projection approximation with ROSIE-PARCS webserver.
Briefings Bioinform.
S. M. Bargeen Alam Turzo, Justin T. Seffernick, Sergey Lyskov, Steffen Lindert
2023 J jnl
Targeting Troponin C with Small Molecules Containing Diphenyl Moieties: Calcium Sensitivity Effects on Striated Muscles and Structure-Activity Relationship.
J. Chem. Inf. Model.
Eric R. Hantz, Svetlana B. Tikunova, Natalya Belevych, Jonathan P. Davis, Peter J. Reiser, Steffen Lindert
2023 J jnl
Umbrella Sampling Simulations of Cardiac Thin Filament Reveal Thermodynamic Consequences of Troponin I Inhibitory Peptide Mutations.
J. Chem. Inf. Model.
Austin M. Cool, Steffen Lindert
2022 J jnl
Actives-Based Receptor Selection Strongly Increases the Success Rate in Structure-Based Drug Design and Leads to Identification of 22 Potent Cancer Inhibitors.
J. Chem. Inf. Model.
Eric R. Hantz, Steffen Lindert
2022 J jnl
Computational Exploration and Characterization of Potential Calcium Sensitizing Mutations in Cardiac Troponin C.
J. Chem. Inf. Model.
Eric R. Hantz, Steffen Lindert
2022 J jnl
Umbrella Sampling Simulations Measure Switch Peptide Binding and Hydrophobic Patch Opening Free Energies in Cardiac Troponin.
J. Chem. Inf. Model.
Austin M. Cool, Steffen Lindert
2021 J jnl
Adaptative Steered Molecular Dynamics Study of Mutagenesis Effects on Calcium Affinity in the Regulatory Domain of Cardiac Troponin C.
J. Chem. Inf. Model.
Eric R. Hantz, Steffen Lindert
2020 J jnl
Discovery of Novel Small-Molecule Calcium Sensitizers for Cardiac Troponin C: A Combined Virtual and Experimental Screening Approach.
J. Chem. Inf. Model.
William H. Coldren, Svetlana B. Tikunova, Jonathan P. Davis, Steffen Lindert
2020 J jnl
Using NMR Chemical Shifts and Cryo-EM Density Restraints in Iterative Rosetta-MD Protein Structure Refinement.
J. Chem. Inf. Model.
Sumudu P. Leelananda, Steffen Lindert
2019 J jnl
Mechanism of Cardiac Troponin C Calcium Sensitivity Modulation by Small Molecules Illuminated by Umbrella Sampling Simulations.
J. Chem. Inf. Model.
Jacob D. Bowman, William H. Coldren, Steffen Lindert
2017 J jnl
Successful Identification of Cardiac Troponin Calcium Sensitizers Using a Combination of Virtual Screening and ROC Analysis of Known Troponin C Binders.
J. Chem. Inf. Model.
Melanie L. Aprahamian, Svetlana B. Tikunova, Morgan V. Price, Andres F. Cuesta, Jonathan P. Davis, Steffen Lindert
2015 J jnl
In silico screening for Plasmodium falciparum enoyl-ACP reductase inhibitors.
J. Comput. Aided Mol. Des.
Steffen Lindert, Lorillee Tallorin, Quynh G. Nguyen, Michael D. Burkart, James Andrew McCammon
2013 J jnl
Computational determination of the orientation of a heat repeat-like domain of DNA-PKcs.
Comput. Biol. Chem.
Steffen Lindert, Phoebe L. Stewart, Jens Meiler
2012 J jnl
Molecular Basis of Calcium-Sensitizing and Desensitizing Mutations of the Human Cardiac Troponin C Regulatory Domain: A Multi-Scale Simulation Study.
PLoS Comput. Biol.
Peter Michael Kekenes-Huskey, Steffen Lindert, James Andrew McCammon