Sheng-Yong Yang

16 papers Journal 16
YearRankTypeTitle / Venue / Authors
2024 J jnl
PocketFlow is a data-and-knowledge-driven structure-based molecular generative model.
Nat. Mac. Intell.
Yuanyuan Jiang, Guo Zhang, Jing You, Hailin Zhang, Rui Yao, Huan-Zhang Xie, Liyun Zhang, Ziyi Xia, Mengzhe Dai, Yunjie Wu, Linli Li, Sheng-Yong Yang
2022 J jnl
Discovery of Small Molecule Agonist of Gonadotropin-Releasing Hormone Receptor (GnRH1R).
J. Chem. Inf. Model.
Xin Yang, Guifeng Lin, Anjie Xia, Jingming Liu, Shiyu Zhang, Pei Zhou, Yiwei Wang, Jiahao Zhang, Yangli Zhou, Pei Chen, Yifei Wang, Tao Zheng, Linli Li, Sheng-Yong Yang
2017 J jnl
Discovery of New SIRT2 Inhibitors by Utilizing a Consensus Docking/Scoring Strategy and Structure-Activity Relationship Analysis.
J. Chem. Inf. Model.
Shenzhen Huang, Chunli Song, Xiang Wang, Guo Zhang, Yanlin Wang, Xiaojuan Jiang, Qizheng Sun, Luyi Huang, Rong Xiang, Yiguo Hu, Linli Li, Sheng-Yong Yang
2017 J jnl
HEROD: a human ethnic and regional specific omics database.
Bioinform.
Xian Zeng, Lin Tao, Peng Zhang, Chu Qin, Shangying Chen, Weidong He, Ying Tan, Hong Xia Liu, Sheng-Yong Yang, Zhe Chen, Yu Yang Jiang, Yuzong Chen
2017 J jnl
IFPTarget: A Customized Virtual Target Identification Method Based on Protein-Ligand Interaction Fingerprinting Analyses.
J. Chem. Inf. Model.
Guo-Bo Li, Zhu-jun Yu, Sha Liu, Lu-Yi Huang, Ling-Ling Yang, Christopher T. Lohans, Sheng-Yong Yang
2017 J jnl
Individualized network-based drug repositioning infrastructure for precision oncology in the panomics era.
Briefings Bioinform.
Feixiong Cheng, Huixiao Hong, Sheng-Yong Yang, Yuquan Wei
2015 J jnl
CFam: a chemical families database based on iterative selection of functional seeds and seed-directed compound clustering.
Nucleic Acids Res.
Cheng Zhang, Lin Tao, Chu Qin, Peng Zhang, Shangying Chen, Xian Zeng, Feng Xu, Zhe Chen, Sheng-Yong Yang, Yuzong Chen
2014 J jnl
A prediction model of drug-induced ototoxicity developed by an optimal support vector machine (SVM) method.
Comput. Biol. Medicine
Shu Zhou, Guo-Bo Li, Lu-Yi Huang, Huan-Zhang Xie, Ying-Lan Zhao, Yuzong Chen, Lin-Li Li, Sheng-Yong Yang
2014 J jnl
Therapeutic target database update 2014: a resource for targeted therapeutics.
Nucleic Acids Res.
Chu Qin, Cheng Zhang, Feng Zhu, Feng Xu, Shangying Chen, Peng Zhang, Ying Hong Li, Sheng-Yong Yang, Yu-Quan Wei, Lin Tao, Yuzong Chen
2013 J jnl
ID-Score: A New Empirical Scoring Function Based on a Comprehensive Set of Descriptors Related to Protein-Ligand Interactions.
J. Chem. Inf. Model.
Guo-Bo Li, Ling-Ling Yang, Wen-Jing Wang, Lin-Li Li, Sheng-Yong Yang
2011 J jnl
A prediction model of substrates and non-substrates of breast cancer resistance protein (BCRP) developed by GA-CG-SVM method.
Comput. Biol. Medicine
Lei Zhong, Chang-Ying Ma, Hui Zhang, Li-Jun Yang, Hua-Lin Wan, Qing-Qing Xie, Lin-Li Li, Sheng-Yong Yang
2011 J jnl
Discovery of Novel Pim-1 Kinase Inhibitors by a Hierarchical Multistage Virtual Screening Approach Based on SVM Model, Pharmacophore, and Molecular Docking.
J. Chem. Inf. Model.
Ji-Xia Ren, Lin-Li Li, Ren-Lin Zheng, Huan-Zhang Xie, Zhi-Xing Cao, Shan Feng, You-Li Pan, Xin Chen, Yu-Quan Wei, Sheng-Yong Yang
2011 J jnl
Effect of training data size and noise level on support vector machines virtual screening of genotoxic compounds from large compound libraries.
J. Comput. Aided Mol. Des.
Pankaj Kumar, Xiaohua Ma, Xianghui Liu, Jia Jia, Bu-Cong Han, Ying Xue, Ze-Rong Li, Sheng-Yong Yang, Yu-Quan Wei, Yuzong Chen
2011 J jnl
RASA: A Rapid Retrosynthesis-Based Scoring Method for the Assessment of Synthetic Accessibility of Drug-like Molecules.
J. Chem. Inf. Model.
Qi Huang, Lin-Li Li, Sheng-Yong Yang
2009 J jnl
An integrated scheme for feature selection and parameter setting in the support vector machine modeling and its application to the prediction of pharmacokinetic properties of drugs.
Artif. Intell. Medicine
Sheng-Yong Yang, Qi Huang, Lin-Li Li, Chang-Ying Ma, Hui Zhang, Ru Bai, Qizhi Teng, Ming-Li Xiang, Yu-Quan Wei
2007 J jnl
Free energy profiles for monomer capture in Grubbs- and SHOP-type olefin polymerization catalysts: A constraint
J. Comput. Chem.
Sheng-Yong Yang, Ming-Li Xiang, Li-Juan Chen, Guo-Bin Xie, Bing Shi, Yu-Quan Wei, Tom Ziegler