Shaoyong Lu

16 papers Journal 16
YearRankTypeTitle / Venue / Authors
2025 J jnl
Deciphering the unique dynamic activation pathway in a G protein-coupled receptor enables unveiling biased signaling and identifying cryptic allosteric sites in conformational intermediates.
CoRR
Jigang Fan, Chunhao Zhu, Xiaobing Lan, Haiming Zhuang, Mingyu Li, Jian Zhang, Shaoyong Lu
2023 J jnl
AlloReverse: multiscale understanding among hierarchical allosteric regulations.
Nucleic Acids Res.
Jinyin Zha, Qian Li, Xinyi Liu, Weidong Lin, Tingting Wang, Jiacheng Wei, Ziliang Zhang, Xun Lu, Jing Wu, Duan Ni, Kun Song, Liang Zhang, Xuefeng Lu, Shaoyong Lu, Jian Zhang
2022 J jnl
Markov State Models and Molecular Dynamics Simulations Reveal the Conformational Transition of the Intrinsically Disordered Hypervariable Region of K-Ras4B to the Ordered Conformation.
J. Chem. Inf. Model.
Hao Zhang, Duan Ni, Jigang Fan, Minyu Li, Jian Zhang, Chen Hua, Ruth Nussinov, Shaoyong Lu
2020 J jnl
Unraveling allosteric landscapes of allosterome with ASD.
Nucleic Acids Res.
Xinyi Liu, Shaoyong Lu, Kun Song, Qiancheng Shen, Duan Ni, Qian Li, Xinheng He, Hao Zhang, Qi Wang, Yingyi Chen, Xinyi Li, Jing Wu, Chunquan Sheng, Guoqiang Chen, Yaqin Liu, Xuefeng Lu, Jian Zhang
2019 J jnl
AlloDriver: a method for the identification and analysis of cancer driver targets.
Nucleic Acids Res.
Kun Song, Qian Li, Wei Gao, Shaoyong Lu, Qiancheng Shen, Xinyi Liu, Yongyan Wu, Binquan Wang, Houwen Lin, Guoqiang Chen, Jian Zhang
2019 J jnl
Are the Apo Proteins Suitable for the Rational Discovery of Allosteric Drugs?
J. Chem. Inf. Model.
Xiaoli An, Shaoyong Lu, Kun Song, Qiancheng Shen, Meilan Huang, Xiaojun Yao, Huanxiang Liu, Jian Zhang
2018 J jnl
AlloFinder: a strategy for allosteric modulator discovery and allosterome analyses.
Nucleic Acids Res.
Min Huang, Kun Song, Xinyi Liu, Shaoyong Lu, Qiancheng Shen, Renxiao Wang, Jingze Gao, Yuanyuan Hong, Qian Li, Duan Ni, Jianrong Xu, Guoqiang Chen, Jian Zhang
2017 J jnl
Improved Method for the Identification and Validation of Allosteric Sites.
J. Chem. Inf. Model.
Kun Song, Xinyi Liu, Wenkang Huang, Shaoyong Lu, Qiancheng Shen, Lu Zhang, Jian Zhang
2016 J jnl
ASD v3.0: unraveling allosteric regulation with structural mechanisms and biological networks.
Nucleic Acids Res.
Qiancheng Shen, Guanqiao Wang, Shuai Li, Xinyi Liu, Shaoyong Lu, Zhongjie Chen, Kun Song, Junhao Yan, Lv Geng, Zhimin Huang, Wenkang Huang, Guoqiang Chen, Jian Zhang
2016 J jnl
Alloscore: a method for predicting allosteric ligand-protein interactions.
Bioinform.
Shuai Li, Qiancheng Shen, Minyi Su, Xinyi Liu, Shaoyong Lu, Zhongjie Chen, Renxiao Wang, Jian Zhang
2015 J jnl
ASBench: benchmarking sets for allosteric discovery.
Bioinform.
Wenkang Huang, Guanqiao Wang, Qiancheng Shen, Xinyi Liu, Shaoyong Lu, Lv Geng, Zhimin Huang, Jian Zhang
2014 J jnl
ASD v2.0: updated content and novel features focusing on allosteric regulation.
Nucleic Acids Res.
Zhimin Huang, Linkai Mou, Qiancheng Shen, Shaoyong Lu, Chuangang Li, Xinyi Liu, Guanqiao Wang, Shuai Li, Lv Geng, Yaqin Liu, Jiawei Wu, Guoqiang Chen, Jian Zhang
2014 J jnl
The Structural Basis of ATP as an Allosteric Modulator.
PLoS Comput. Biol.
Shaoyong Lu, Wenkang Huang, Qi Wang, Qiancheng Shen, Shuai Li, Ruth Nussinov, Jian Zhang
2013 J jnl
Allosite: a method for predicting allosteric sites.
Bioinform.
Wenkang Huang, Shaoyong Lu, Zhimin Huang, Xinyi Liu, Linkai Mou, Yu Luo, Yanlong Zhao, Yaqin Liu, Zhongjie Chen, Tingjun Hou, Jian Zhang
2013 J jnl
Exploring the Desumoylation Process of SENP1: A Study Combined MD Simulations with QM/MM Calculations on SENP1-SUMO1-RanGAP1.
J. Chem. Inf. Model.
Ting Shi, Yuhui Han, Weihua Li, Yanlong Zhao, Yaqin Liu, Zhimin Huang, Shaoyong Lu, Jian Zhang
2012 J jnl
Insights into the Role of Magnesium Triad in
J. Chem. Inf. Model.
Shaoyong Lu, Wenkang Huang, Xiaobai Li, Zhimin Huang, Xinyi Liu, Yingyi Chen, Ting Shi, Jian Zhang