Peichen Pan

54 papers A* 5A 7C 2Misc 2Journal 35
YearRankTypeTitle / Venue / Authors
2026 J jnl
NavDB: A Comprehensive Database for Voltage-Gated Sodium Channels Modulators and Targets.
J. Chem. Inf. Model.
Gaoang Wang, Jiahui Yu, Haiyi Chen, Hao Luo, Peichen Pan, Tingjun Hou
2025 J jnl
ADMET evaluation in drug discovery: 21. Application and industrial validation of machine learning algorithms for Caco-2 permeability prediction.
J. Cheminformatics
Dong Wang, Jieyu Jin, Guqin Shi, Jingxiao Bao, Zheng Wang, Shimeng Li, Peichen Pan, Dan Li, Yu Kang, Tingjun Hou
2025 J jnl
Deep Learning-Driven Insights into Enzyme-Substrate Interaction Discovery.
J. Chem. Inf. Model.
Wenjia Qian, Xiaorui Wang, Yuansheng Huang, Yu Kang, Peichen Pan, Chang-Yu Hsieh, Tingjun Hou
2025 J jnl
Deep lead optimization enveloped in protein pocket and its application in designing potent and selective ligands targeting LTK protein.
Nat. Mac. Intell.
Shicheng Chen, Odin Zhang, Chenran Jiang, Huifeng Zhao, Xujun Zhang, Mengting Chen, Yun Liu, Qun Su, Zhenxing Wu, Xinyue Wang, Wanglin Qu, Yuanyi Ye, Xin Chai, Ning Wang, Tianyue Wang, Yuan An, Guanlin Wu, Qianqian Yang, Jiean Chen, Wei Xie, Haitao Lin, Dan Li, Chang-Yu Hsieh, Yong Huang, Yu Kang, Tingjun Hou, Peichen Pan
2025 J jnl
ECloudGen: leveraging electron clouds as a latent variable to scale up structure-based molecular design.
Nat. Comput. Sci.
Odin Zhang, Jieyu Jin, Zhenxing Wu, Jintu Zhang, Po Yuan, Yuntao Yu, Haitao Lin, Haiyang Zhong, Xujun Zhang, Chenqing Hua, Weibo Zhao, Zhengshuo Zhang, Kejun Ying, Yufei Huang, Huifeng Zhao, Yu Kang, Peichen Pan, Jike Wang, Dong Guo, Shuangjia Zheng, Chang-Yu Hsieh, Tingjun Hou
2024 J jnl
A general model for predicting enzyme functions based on enzymatic reactions.
J. Cheminformatics
Wenjia Qian, Xiaorui Wang, Yu Kang, Peichen Pan, Tingjun Hou, Chang-Yu Hsieh
2024 J jnl
Comprehensive assessment of protein loop modeling programs on large-scale datasets: prediction accuracy and efficiency.
Briefings Bioinform.
Tianyue Wang, Langcheng Wang, Xujun Zhang, Chao Shen, Odin Zhang, Jike Wang, Jialu Wu, Ruofan Jin, Donghao Zhou, Shicheng Chen, Liwei Liu, Xiaorui Wang, Chang-Yu Hsieh, Guangyong Chen, Peichen Pan, Yu Kang, Tingjun Hou
2024 J jnl
Deep Geometry Handling and Fragment-wise Molecular 3D Graph Generation.
CoRR
Odin Zhang, Yufei Huang, Shichen Cheng, Mengyao Yu, Xujun Zhang, Haitao Lin, Yundian Zeng, Mingyang Wang, Zhenxing Wu, Huifeng Zhao, Zaixi Zhang, Chenqing Hua, Yu Kang, Sunliang Cui, Peichen Pan, Chang-Yu Hsieh, Tingjun Hou
2024 J jnl
Deep Lead Optimization: Leveraging Generative AI for Structural Modification.
CoRR
Odin Zhang, Haitao Lin, Hui Zhang, Huifeng Zhao, Yufei Huang, Yuansheng Huang, Dejun Jiang, Chang-Yu Hsieh, Peichen Pan, Tingjun Hou
2024 J jnl
Dissecting the role of ALK double mutations in drug resistance to lorlatinib with in-depth theoretical modeling and analysis.
Comput. Biol. Medicine
Xing Zhang, Jianbo Tong, Tianhao Wang, Tianyue Wang, Lei Xu, Zhe Wang, Tingjun Hou, Peichen Pan
2024 J jnl
Genetic Algorithm-Based Receptor Ligand: A Genetic Algorithm-Guided Generative Model to Boost the Novelty and Drug-Likeness of Molecules in a Sampling Chemical Space.
J. Chem. Inf. Model.
Mingyang Wang, Zhengjian Wu, Jike Wang, Gaoqi Weng, Yu Kang, Peichen Pan, Dan Li, Yafeng Deng, Xiaojun Yao, Zhitong Bing, Chang-Yu Hsieh, Tingjun Hou
2024 J jnl
In-depth theoretical modeling to explore the mechanism of TPX-0131 overcoming lorlatinib resistance to ALKL1196M/G1202R mutation.
Comput. Biol. Medicine
Xing Zhang, Jianbo Tong, Tianhao Wang, Zhe Wang, Shukai Gu, Lei Xu, Tingjun Hou, Peichen Pan
2024 J jnl
Structure-based virtual screening of novel USP5 inhibitors targeting the zinc finger ubiquitin-binding domain.
Comput. Biol. Medicine
Tianhao Wang, Jianbo Tong, Xing Zhang, Zhe Wang, Lei Xu, Peichen Pan, Tingjun Hou
2023 J jnl
Efficient and accurate large library ligand docking with KarmaDock.
Nat. Comput. Sci.
Xujun Zhang, Odin Zhang, Chao Shen, Wanglin Qu, Shicheng Chen, Hanqun Cao, Yu Kang, Zhe Wang, Ercheng Wang, Jintu Zhang, Yafeng Deng, Furui Liu, Tianyue Wang, Hongyan Du, Langcheng Wang, Peichen Pan, Guangyong Chen, Chang-Yu Hsieh, Tingjun Hou
2023 J jnl
Learning on topological surface and geometric structure for 3D molecular generation.
Nat. Comput. Sci.
Odin Zhang, Tianyue Wang, Gaoqi Weng, Dejun Jiang, Ning Wang, Xiaorui Wang, Huifeng Zhao, Jialu Wu, Ercheng Wang, Guangyong Chen, Yafeng Deng, Peichen Pan, Yu Kang, Chang-Yu Hsieh, Tingjun Hou
2023 J jnl
ML-PLIC: a web platform for characterizing protein-ligand interactions and developing machine learning-based scoring functions.
Briefings Bioinform.
Xujun Zhang, Chao Shen, Tianyue Wang, Yafeng Deng, Yu Kang, Dan Li, Tingjun Hou, Peichen Pan
2023 J jnl
Small-Molecule Conformer Generators: Evaluation of Traditional Methods and AI Models on High-Quality Data Sets.
J. Chem. Inf. Model.
Zhe Wang, Haiyang Zhong, Jintu Zhang, Peichen Pan, Dong Wang, Huanxiang Liu, Xiaojun Yao, Tingjun Hou, Yu Kang
2023 J jnl
TB-IECS: an accurate machine learning-based scoring function for virtual screening.
J. Cheminformatics
Xujun Zhang, Chao Shen, Dejun Jiang, Jintu Zhang, Qing Ye, Lei Xu, Tingjun Hou, Peichen Pan, Yu Kang
2022 J jnl
FPGA HLS Today: Successes, Challenges, and Opportunities.
ACM Trans. Reconfigurable Technol. Syst.
Jason Cong, Jason Lau, Gai Liu, Stephen Neuendorffer, Peichen Pan, Kees A. Vissers, Zhiru Zhang
2022 J jnl
ReMODE: a deep learning-based web server for target-specific drug design.
J. Cheminformatics
Mingyang Wang, Jike Wang, Gaoqi Weng, Yu Kang, Peichen Pan, Dan Li, Yafeng Deng, Honglin Li, Chang-Yu Hsieh, Tingjun Hou
2022 J jnl
VGSC-DB: an online database of voltage-gated sodium channels.
J. Cheminformatics
Gaoang Wang, Jiahui Yu, Hongyan Du, Chao Shen, Xujun Zhang, Yifei Liu, Yangyang Zhang, Dong-Sheng Cao, Peichen Pan, Tingjun Hou
2019 J jnl
Caffeine: Toward Uniformed Representation and Acceleration for Deep Convolutional Neural Networks.
IEEE Trans. Comput. Aided Des. Integr. Circuits Syst.
Chen Zhang, Guangyu Sun, Zhenman Fang, Peipei Zhou, Peichen Pan, Jason Cong
2017 J jnl
Comparative analyses of structural features and scaffold diversity for purchasable compound libraries.
J. Cheminformatics
Jun Shang, Huiyong Sun, Hui Liu, Fu Chen, Sheng Tian, Peichen Pan, Dan Li, De-Xin Kong, Tingjun Hou
2016 A conf
Caffeine: towards uniformed representation and acceleration for deep convolutional neural networks.
ICCAD
Chen Zhang, Zhenman Fang, Peipei Zhou, Peichen Pan, Jason Cong
2016 — ch.
Sequential Circuit Technology Mapping.
Encyclopedia of Algorithms
Peichen Pan
2016 A conf
Software Infrastructure for Enabling FPGA-Based Accelerations in Data Centers: Invited Paper.
ISLPED
Jason Cong, Muhuan Huang, Peichen Pan, Di Wu, Peng Zhang
2016 — ch.
Source-to-Source Optimization for HLS.
FPGAs for Software Programmers
Jason Cong, Muhuan Huang, Peichen Pan, Yuxin Wang, Peng Zhang
2015 J jnl
Identification and Preliminary SAR Analysis of Novel Type-I Inhibitors of TIE-2 via Structure-Based Virtual Screening and Biological Evaluation in in vitro Models.
J. Chem. Inf. Model.
Peichen Pan, Sheng Tian, Huiyong Sun, Xiaotian Kong, Wenfang Zhou, Dan Li, Youyong Li, Tingjun Hou
2014 J jnl
Assessing an Ensemble Docking-Based Virtual Screening Strategy for Kinase Targets by Considering Protein Flexibility.
J. Chem. Inf. Model.
Sheng Tian, Huiyong Sun, Peichen Pan, Dan Li, Xuechu Zhen, Youyong Li, Tingjun Hou
2013 J jnl
Development and Evaluation of an Integrated Virtual Screening Strategy by Combining Molecular Docking and Pharmacophore Searching Based on Multiple Protein Structures.
J. Chem. Inf. Model.
Sheng Tian, Huiyong Sun, Youyong Li, Peichen Pan, Dan Li, Tingjun Hou
2013 J jnl
Molecular Principle of Topotecan Resistance by Topoisomerase I Mutations through Molecular Modeling Approaches.
J. Chem. Inf. Model.
Peichen Pan, Youyong Li, Huidong Yu, Huiyong Sun, Tingjun Hou
2008 — ch.
Sequential Circuit Technology Mapping.
Encyclopedia of Algorithms
Peichen Pan
2006 J jnl
FPGA Design Automation: A Survey.
Found. Trends Electron. Des. Autom.
Deming Chen, Jason Cong, Peichen Pan
2002 J jnl
Monotone bipartitioning problem in a planar point set with applications to VLSI.
ACM Trans. Design Autom. Electr. Syst.
Parthasarathi Dasgupta, Peichen Pan, Subhas C. Nandy, Bhargab B. Bhattacharya
1999 Misc conf
Optimal Retiming for Initial State Computation.
VLSI Design
Peichen Pan, Guohua Chen
1999 J jnl
Partial Scan with Preselected Scan Signals.
IEEE Trans. Computers
Peichen Pan, C. L. Liu
1999 A* conf
Performance-Driven Integration of Retiming and Resynthesis.
DAC
Peichen Pan
1999 Misc conf
The Retiming of Single-Phase Clocked Circuits Containing Level-Sensitive Latches.
VLSI Design
Prashant Saxena, Peichen Pan, C. L. Liu
1998 A conf
A New Retiming-Based Technology Mapping Algorithm for LUT-based FPGAs.
FPGA
Peichen Pan, Chih-Chang Lin
1998 A conf
Low power logic synthesis under a general delay model.
ISLPED
Unni Narayanan, Peichen Pan, C. L. Liu
1998 J jnl
Optimal clock period FPGA technology mapping for sequential circuits.
ACM Trans. Design Autom. Electr. Syst.
Peichen Pan, C. L. Liu
1998 J jnl
Optimal clock period clustering for sequential circuits with retiming.
IEEE Trans. Comput. Aided Des. Integr. Circuits Syst.
Peichen Pan, Arvind K. Karandikar, C. L. Liu
1997 C conf
Continuous Retiming: Algorithms and Applications.
ICCD
Peichen Pan
1997 C conf
Optimal Clock Period Clustering for Sequential Circuits with Retiming.
ICCD
Arvind K. Karandikar, Peichen Pan, C. L. Liu
1997 J jnl
Optimal Graph Constraint Reduction for Symbolic Layout Compaction.
Algorithmica
Peichen Pan, Sai-keung Dong, C. L. Liu
1996 J jnl
Area Minimization for Hierarchical Floorplans.
Algorithmica
Peichen Pan, Weiping Shi, C. L. Liu
1996 A* conf
Desensitization for Power Reduction in Sequential Circuits.
DAC
Xiangfeng Chen, Peichen Pan, C. L. Liu
1996 A* conf
Optimal Clock Period FPGA Technology Mapping for Sequential Circuits.
DAC
Peichen Pan, C. L. Liu
1996 A conf
Technology Mapping of Sequential Circuits for LUT-Based FPGAs for Performance.
FPGA
Peichen Pan, C. L. Liu
1995 J jnl
Area minimization for floorplans.
IEEE Trans. Comput. Aided Des. Integr. Circuits Syst.
Peichen Pan, C. L. Liu
1995 A* conf
Partial Scan with Pre-selected Scan Signals.
DAC
Peichen Pan, C. L. Liu
1994 A conf
Area minimization for hierarchical floorplans.
ICCAD
Peichen Pan, Weiping Shi, C. L. Liu
1993 A* conf
Optimal Graph Constraint Reduction for Symbolic Layout Compaction.
DAC
Peichen Pan, Sai-keung Dong, C. L. Liu
1992 A conf
Area minimization for general floorplans.
ICCAD
Peichen Pan, C. L. Liu