Pak Chung Sham

36 papers Journal 35Unranked 1
YearRankTypeTitle / Venue / Authors
2024 J jnl
Estimation of causal effects of genes on complex traits using a Bayesian-network-based framework applied to GWAS data.
Nat. Mac. Intell.
Liangying Yin, Yaning Feng, Yujia Shi, Alexandria Lau, Jinghong Qiu, Pak Chung Sham, Hon-Cheong So
2023 J jnl
Inferring CTCF-binding patterns and anchored loops across human tissues and cell types.
Patterns
Hang Xu, Xianfu Yi, Xutong Fan, Chengyue Wu, Wei Wang, Xinlei Chu, Shijie Zhang, Xiaobao Dong, Zhao Wang, Jianhua Wang, Yao Zhou, Ke Zhao, Hongcheng Yao, Nan Zheng, Junwen Wang, Yupeng Chen, Dariusz Plewczynski, Pak Chung Sham, Kexin Chen, Dandan Huang, Mulin Jun Li
2022 J jnl
VannoPortal: multiscale functional annotation of human genetic variants for interrogating molecular mechanism of traits and diseases.
Nucleic Acids Res.
Dandan Huang, Yao Zhou, Xianfu Yi, Xutong Fan, Jianhua Wang, Hongcheng Yao, Pak Chung Sham, Jihui Hao, Kexin Chen, Mulin Jun Li
2021 J jnl
A framework to decipher the genetic architecture of combinations of complex diseases: applications in cardiovascular medicine.
Bioinform.
Liangying Yin, Carlos Kwan-Long Chau, Yu-Ping Lin, Shitao Rao, Yong Xiang, Pak Chung Sham, Hon-Cheong So
2021 J jnl
vSampler: fast and annotation-based matched variant sampling tool.
Bioinform.
Dandan Huang, Zhao Wang, Yao Zhou, Qian Liang, Pak Chung Sham, Hongcheng Yao, Mulin Jun Li
2020 J jnl
CAUSALdb: a database for disease/trait causal variants identified using summary statistics of genome-wide association studies.
Nucleic Acids Res.
Jianhua Wang, Dandan Huang, Yao Zhou, Hongcheng Yao, Huanhuan Liu, Sinan Zhai, Chengwei Wu, Zhanye Zheng, Ke Zhao, Zhao Wang, Xianfu Yi, Shijie Zhang, Xiaorong Liu, Zipeng Liu, Kexin Chen, Ying Yu, Pak Chung Sham, Mulin Jun Li
2020 J jnl
Methods and resources to access mutation-dependent effects on cancer drug treatment.
Briefings Bioinform.
Hongcheng Yao, Qian Liang, Xinyi Qian, Junwen Wang, Pak Chung Sham, Mulin Jun Li
2020 J jnl
QTLbase: an integrative resource for quantitative trait loci across multiple human molecular phenotypes.
Nucleic Acids Res.
Zhanye Zheng, Dandan Huang, Jianhua Wang, Ke Zhao, Yao Zhou, Zhenyang Guo, Sinan Zhai, Hang Xu, Hui Cui, Hongcheng Yao, Zhao Wang, Xianfu Yi, Shijie Zhang, Pak Chung Sham, Mulin Jun Li
2019 J jnl
A powerful conditional gene-based association approach implicated functionally important genes for schizophrenia.
Bioinform.
Miao-Xin Li, Lin Jiang, Timothy Shin Heng Mak, Johnny S. H. Kwan, Chao Xue, Peikai Chen, Henry Chi-Ming Leung, Liqian Cui, Tao Li, Pak Chung Sham
2019 J jnl
Evaluation of tools for highly variable gene discovery from single-cell RNA-seq data.
Briefings Bioinform.
Shun H. Yip, Pak Chung Sham, Junwen Wang
2018 J jnl
A powerful approach reveals numerous expression quantitative trait haplotypes in multiple tissues.
Bioinform.
Dingge Ying, Mulin Jun Li, Pak Chung Sham, Miao-Xin Li
2018 J jnl
GWAS4D: multidimensional analysis of context-specific regulatory variant for human complex diseases and traits.
Nucleic Acids Res.
Dandan Huang, Xianfu Yi, Shijie Zhang, Zhanye Zheng, Panwen Wang, Chenghao Xuan, Pak Chung Sham, Junwen Wang, Mulin Jun Li
2017 J jnl
mTCTScan: a comprehensive platform for annotation and prioritization of mutations affecting drug sensitivity in cancers.
Nucleic Acids Res.
Mulin Jun Li, Hongcheng Yao, Dandan Huang, Huanhuan Liu, Zipeng Liu, Hang Xu, Yiming Qin, Jeanette Prinz, Weiyi Xia, Panwen Wang, Bin Yan, Nhan L. Tran, Jean-Pierre A. Kocher, Pak Chung Sham, Junwen Wang
2016 J jnl
GWASdb v2: an update database for human genetic variants identified by genome-wide association studies.
Nucleic Acids Res.
Mulin Jun Li, Zipeng Liu, Panwen Wang, Maria P. Wong, Matthew R. Nelson, Jean-Pierre A. Kocher, Meredith Yeager, Pak Chung Sham, Stephen J. Chanock, Zhengyuan Xia, Junwen Wang
2016 J jnl
Inheritance-mode specific pathogenicity prioritization (ISPP) for human protein coding genes.
Bioinform.
Jacob Shujui Hsu, Johnny S. H. Kwan, Zhicheng Pan, Maria-Mercè Garcia-Barcelo, Pak Chung Sham, Miao-Xin Li
2016 J jnl
Predicting regulatory variants with composite statistic.
Bioinform.
Mulin Jun Li, Zhicheng Pan, Zipeng Liu, Jiexing Wu, Panwen Wang, Yun Zhu, Feng Xu, Zhengyuan Xia, Pak Chung Sham, Jean-Pierre A. Kocher, Miao-Xin Li, Jun S. Liu, Junwen Wang
2015 J jnl
Exploring the function of genetic variants in the non-coding genomic regions: approaches for identifying human regulatory variants affecting gene expression.
Briefings Bioinform.
Mulin Jun Li, Bin Yan, Pak Chung Sham, Junwen Wang
2015 J jnl
MGAS: a powerful tool for multivariate gene-based genome-wide association analysis.
Bioinform.
Sophie Van der Sluis, Conor V. Dolan, Jiang Li, You-Qiang Song, Pak Chung Sham, Danielle Posthuma, Miao-Xin Li
2014 J jnl
dbPSHP: a database of recent positive selection across human populations.
Nucleic Acids Res.
Mulin Jun Li, Lily Yan Wang, Zhengyuan Xia, Maria P. Wong, Pak Chung Sham, Junwen Wang
2013 J jnl
GWAS3D: detecting human regulatory variants by integrative analysis of genome-wide associations, chromosome interactions and histone modifications.
Nucleic Acids Res.
Mulin Jun Li, Lily Yan Wang, Zhengyuan Xia, Pak Chung Sham, Junwen Wang
2012 J jnl
GWASdb: a database for human genetic variants identified by genome-wide association studies.
Nucleic Acids Res.
Mulin Jun Li, Panwen Wang, Xiaorong Liu, Ee Lyn Lim, Zhangyong Wang, Meredith Yeager, Maria P. Wong, Pak Chung Sham, Stephen J. Chanock, Junwen Wang
2011 J jnl
Correlated evolution of transcription factors and their binding sites.
Bioinform.
Shu Yang, Hari Krishna Yalamanchili, Xinran Li, Kwok-Ming Yao, Pak Chung Sham, Michael Q. Zhang, Junwen Wang
2010 J jnl
FastPval: a fast and memory efficient program to calculate very low
Bioinform.
Mulin Jun Li, Pak Chung Sham, Junwen Wang
2010 J jnl
SKM-SNP: SNP markers detection method.
J. Biomed. Informatics
Yang Liu, Mark Junjie Li, Yiu-ming Cheung, Pak Chung Sham, Michael K. Ng
2009 J jnl
IGG3: a tool to rapidly integrate large genotype datasets for whole-genome imputation and individual-level meta-analysis.
Bioinform.
Miao-Xin Li, Lin Jiang, Patrick Yu-Ping Kao, Pak Chung Sham, You-Qiang Song
2008 J jnl
Unidimensional nonnegative scaling for genome-wide Linkage Disequilibrium maps.
Int. J. Bioinform. Res. Appl.
Haiyong Liao, Michael K. Ng, Eric S. Fung, Pak Chung Sham
2007 J jnl
Combining functional and linkage disequilibrium information in the selection of tag SNPs.
Bioinform.
Pak Chung Sham, Sio Iong Ao, Johnny S. H. Kwan, P. Kao, F. Cheung, Pui-Yee Fong, Michael K. Ng
2007 J jnl
Constrained unidimensional scaling with application to genomics.
Comput. Stat. Data Anal.
Sio Iong Ao, Michael K. Ng, Pak Chung Sham
2007 J jnl
IGG: A tool to integrate GeneChips for genetic studies.
Bioinform.
Miao-Xin Li, Lin Jiang, S.-L. Ho, You-Qiang Song, Pak Chung Sham
2007 J jnl
WHAP: haplotype-based association analysis.
Bioinform.
Shaun Purcell, Mark J. Daly, Pak Chung Sham
2006 — conf
Clustering of SNP Data with Application to Genomics.
ICDM Workshops
Michael K. Ng, Mark Junjie Li, Sio Iong Ao, Pak Chung Sham, Yiu-ming Cheung, Joshua Zhexue Huang
2005 J jnl
CLUSTAG: hierarchical clustering and graph methods for selecting tag SNPs.
Bioinform.
Sio Iong Ao, Kevin Y. Yip, Michael K. Ng, David Wai-Lok Cheung, Pui-Yee Fong, Ian Melhado, Pak Chung Sham
2003 J jnl
Generic number systems and haplotype analysis.
Comput. Methods Programs Biomed.
Jing Hua Zhao, Pak Chung Sham
2003 J jnl
Genetic Power Calculator: design of linkage and association genetic mapping studies of complex traits.
Bioinform.
Shaun Purcell, Stacey S. Cherny, Pak Chung Sham
2002 J jnl
Analytic approaches to twin data using structural equation models.
Briefings Bioinform.
F. V. Rijsdijk, Pak Chung Sham
2002 J jnl
GENECOUNTING: haplotype analysis with missing genotypes.
Bioinform.
Jing Hua Zhao, Sebastien Lissarrague, Laurent Essioux, Pak Chung Sham