Nicholas Furnham

12 papers Journal 12
YearRankTypeTitle / Venue / Authors
2024 J jnl
Optimisation-based modelling for explainable lead discovery in malaria.
Artif. Intell. Medicine
Yutong Li, Jonathan Cardoso-Silva, John M. Kelly, Michael J. Delves, Nicholas Furnham, Lazaros G. Papageorgiou, Sophia Tsoka
2018 J jnl
Computationally-guided drug repurposing enables the discovery of kinase targets and inhibitors as new schistosomicidal agents.
PLoS Comput. Biol.
Sandra Giuliani, Arthur C. Silva, Joyce Villa Verde Bastos Borba, Pablo I. P. Ramos, Ross A. Paveley, Eugene N. Muratov, Carolina Horta Andrade, Nicholas Furnham
2018 J jnl
Mechanism and Catalytic Site Atlas (M-CSA): a database of enzyme reaction mechanisms and active sites.
Nucleic Acids Res.
António J. M. Ribeiro, Gemma L. Holliday, Nicholas Furnham, Jonathan D. Tyzack, Katherine Ferris, Janet M. Thornton
2016 J jnl
FunTree: advances in a resource for exploring and contextualising protein function evolution.
Nucleic Acids Res.
Ian Sillitoe, Nicholas Furnham
2016 J jnl
QSAR-Driven Discovery of Novel Chemical Scaffolds Active against
J. Chem. Inf. Model.
Cleber C. Melo-Filho, Rafael Ferreira Dantas, Rodolpho C. Braga, Bruno Junior Neves, Mario R. Senger, Walter C. G. Valente, João M. Rezende-Neto, Willian T. Chaves, Eugene N. Muratov, Ross A. Paveley, Nicholas Furnham, Lee Kamentsky, Anne E. Carpenter, Floriano Silva-Junior, Carolina Horta Andrade
2015 J jnl
CATH: comprehensive structural and functional annotations for genome sequences.
Nucleic Acids Res.
Ian Sillitoe, Tony E. Lewis, Alison L. Cuff, Sayoni Das, Paul Ashford, Natalie L. Dawson, Nicholas Furnham, Roman A. Laskowski, David A. Lee, Jonathan G. Lees, Sonja Lehtinen, Romain A. Studer, Janet M. Thornton, Christine A. Orengo
2015 J jnl
Comparisons of Allergenic and Metazoan Parasite Proteins: Allergy the Price of Immunity.
PLoS Comput. Biol.
Nidhi Tyagi, Edward J. Farnell, Colin M. Fitzsimmons, Stephanie Ryan, Edridah M. Tukahebwa, Rick M. Maizels, David W. Dunne, Janet M. Thornton, Nicholas Furnham
2014 J jnl
The Catalytic Site Atlas 2.0: cataloging catalytic sites and residues identified in enzymes.
Nucleic Acids Res.
Nicholas Furnham, Gemma L. Holliday, Tjaart A. P. de Beer, Julius O. B. Jacobsen, William R. Pearson, Janet M. Thornton
2013 J jnl
New functional families (FunFams) in CATH to improve the mapping of conserved functional sites to 3D structures.
Nucleic Acids Res.
Ian Sillitoe, Alison L. Cuff, Benoit H. Dessailly, Natalie L. Dawson, Nicholas Furnham, David A. Lee, Jonathan G. Lees, Tony E. Lewis, Romain A. Studer, Robert Rentzsch, Corin Yeats, Janet M. Thornton, Christine A. Orengo
2012 J jnl
Exploring the Evolution of Novel Enzyme Functions within Structurally Defined Protein Superfamilies.
PLoS Comput. Biol.
Nicholas Furnham, Ian Sillitoe, Gemma L. Holliday, Alison L. Cuff, Roman A. Laskowski, Christine A. Orengo, Janet M. Thornton
2012 J jnl
FunTree: a resource for exploring the functional evolution of structurally defined enzyme superfamilies.
Nucleic Acids Res.
Nicholas Furnham, Ian Sillitoe, Gemma L. Holliday, Alison L. Cuff, Syed Asad Rahman, Roman A. Laskowski, Christine A. Orengo, Janet M. Thornton
2011 J jnl
Extending CATH: increasing coverage of the protein structure universe and linking structure with function.
Nucleic Acids Res.
Alison L. Cuff, Ian Sillitoe, Tony E. Lewis, Andrew B. Clegg, Robert Rentzsch, Nicholas Furnham, Marialuisa Pellegrini-Calace, David T. Jones, Janet M. Thornton, Christine A. Orengo