Li Xie

11 papers Journal 10Unranked 1
YearRankTypeTitle / Venue / Authors
2023 J jnl
Elucidation of genome-wide understudied proteins targeted by PROTAC-induced degradation using interpretable machine learning.
PLoS Comput. Biol.
Li Xie, Lei Xie
2023 J jnl
End-to-end sequence-structure-function meta-learning predicts genome-wide chemical-protein interactions for dark proteins.
PLoS Comput. Biol.
Tian Cai, Li Xie, Shuo Zhang, Muge Chen, Di He, Amitesh Badkul, Yang Liu, Hari Krishna Namballa, Michael Dorogan, Wayne W. Harding, Cameron Mura, Philip E. Bourne, Lei Xie
2023 J jnl
Learning Universal and Robust 3D Molecular Representations with Graph Convolutional Networks.
CoRR
Shuo Zhang, Yang Liu, Li Xie, Lei Xie
2021 J jnl
Exploration of Dark Chemical Genomics Space via Portal Learning: Applied to Targeting the Undruggable Genome and COVID-19 Anti-Infective Polypharmacology.
CoRR
Tian Cai, Li Xie, Muge Chen, Yang Liu, Di He, Shuo Zhang, Cameron Mura, Philip E. Bourne, Lei Xie
2014 J jnl
Towards Structural Systems Pharmacology to Study Complex Diseases and Personalized Medicine.
PLoS Comput. Biol.
Lei Xie, Xiaoxia Ge, Hepan Tan, Li Xie, Yinliang Zhang, Thomas Hart, Xiaowei Yang, Philip E. Bourne
2012 — conf
An integrated workflow for proteome-wide off-target identification and polypharmacology drug design.
BIBM Workshops
Thomas Evangelidis, Philip E. Bourne, Li Xie, Lei Xie
2011 J jnl
Drug Discovery Using Chemical Systems Biology: Weak Inhibition of Multiple Kinases May Contribute to the Anti-Cancer Effect of Nelfinavir.
PLoS Comput. Biol.
Li Xie, Thomas Evangelidis, Lei Xie, Philip E. Bourne
2010 J jnl
Drug Off-Target Effects Predicted Using Structural Analysis in the Context of a Metabolic Network Model.
PLoS Comput. Biol.
Roger L. Chang, Li Xie, Lei Xie, Philip E. Bourne, Bernhard Ø. Palsson
2010 J jnl
The
PLoS Comput. Biol.
Sarah L. Kinnings, Li Xie, Kingston H. Fung, Richard M. Jackson, Lei Xie, Philip E. Bourne
2009 J jnl
A unified statistical model to support local sequence order independent similarity searching for ligand-binding sites and its application to genome-based drug discovery.
Bioinform.
Lei Xie, Li Xie, Philip E. Bourne
2009 J jnl
Drug Discovery Using Chemical Systems Biology: Identification of the Protein-Ligand Binding Network To Explain the Side Effects of CETP Inhibitors.
PLoS Comput. Biol.
Li Xie, Jerry Li, Lei Xie, Philip E. Bourne