Julio Gomis-Tena

14 papers C 1Journal 9Unranked 3
YearRankTypeTitle / Venue / Authors
2025 J jnl
A simulation study of the impact of drug-IKr binding mechanisms on biomarkers of proarrhythmic risk reveals a crucial role in reverse use-dependence of action potential duration and a marked influence on the vulnerable window.
Comput. Methods Programs Biomed.
Julio Gomis-Tena, Fernando Escobar, Lucía Romero
2024 J jnl
Experimentally validated modeling of dynamic drug-hERG channel interactions reproducing the binding mechanisms and its importance in action potential duration.
Comput. Methods Programs Biomed.
Fernando Escobar, Soren Friis, Nouran Adly, Nina Brinkwirth, Julio Gomis-Tena, Javier Saiz, Dan A. Klaerke, Sonja Stoelzle-Feix, Lucía Romero
2024 J jnl
Muscle Network Connectivity Study in Diabetic Peripheral Neuropathy Patients.
Sensors
Isabel Junquera-Godoy, Jose L. Martinez-de-Juan, Gemma González-Lorente, José Miguel Carot-Sierra, Julio Gomis-Tena, Javier Saiz, Silvia García-Blasco, Isabel Pertusa-Mazón, Esther Soler-Climent, Gema Prats-Boluda
2023 C conf
Evaluation of Surface Electromyography Parameters as Possible Biomarkers for the Assessment of Sarcopenia.
BIBE
Isabel Junquera-Godoy, Julio Gomis-Tena, Javier Saiz, Jose L. Martinez-de-Juan, José Miguel Carot-Sierra, Gema Prats-Boluda
2022 J jnl
Automatic modeling of dynamic drug-hERG channel interactions using three voltage protocols and machine learning techniques: A simulation study.
Comput. Methods Programs Biomed.
Fernando Escobar, Julio Gomis-Tena, Javier Saiz, Lucía Romero
2020 J jnl
In Silico Classifiers for the Assessment of Drug Proarrhythmicity.
J. Chem. Inf. Model.
Jordi Llopis-Lorente, Julio Gomis-Tena, Jordi Cano, Lucía Romero, Javier Saiz, Beatriz Trénor
2020 — conf
Prediction of IKr Blocker Channel State Preference Based on Voltage Clamp Simulations Using Machine Learning Techniques.
CinC
Fernando Escobar, Julio Gomis-Tena, Javier Saiz, Lucía Romero
2020 J jnl
When Does the IC50 Accurately Assess the Blocking Potency of a Drug?
J. Chem. Inf. Model.
Julio Gomis-Tena, Brandon M. Brown, Jordi Cano, Beatriz Trénor, Pei-Chi Yang, Javier Saiz, Colleen E. Clancy, Lucía Romero
2018 — conf
Development and Validation of an In Silico Rabbit Purkinje Cell Action Potential Model: A Step Towards a Drug Safety Testing Tool.
CinC
Jordi Cano, Julio Gomis-Tena, Alexander Amberg, Lennart Anger, Véronique Ballet, Jean-Michel Guillon, Manuel Pastor, Ferran Sanz, Lucía Romero, Javier Saiz
2018 J jnl
In Silico QT and APD Prolongation Assay for Early Screening of Drug-Induced Proarrhythmic Risk.
J. Chem. Inf. Model.
Lucía Romero, Jordi Cano, Julio Gomis-Tena, Beatriz Trénor, Ferran Sanz, Manuel Pastor, Javier Saiz
2013 — conf
Deactivation of Per-Arnt-Sim Domain Mutation Increases the Proarrhythmic Risk of Dofetilide.
CinC
Rodolfo Gonzalez, Edgar Cardenas, Alain Manzo-Martinez, Fernando Martinez, Julio Gomis-Tena, Javier Saiz
2011 J jnl
A Multiscale Simulation System for the Prediction of Drug-Induced Cardiotoxicity.
J. Chem. Inf. Model.
Cristian Obiol-Pardo, Julio Gomis-Tena, Ferran Sanz, Javier Saiz, Manuel Pastor
2011 J jnl
Effects of the Antiarrhythmic Drug Dofetilide on Transmural Dispersion of Repolarization in Ventriculum. A Computer Modeling Study.
IEEE Trans. Biomed. Eng.
Javier Saiz, Julio Gomis-Tena, Marta Monserrat, Jose Maria Ferrero, Karen Cardona, Javier Chorro
2009 — ch.
A New Protocol Test For Physical Activity Research In Obese Children (Etiobe Project).
Annual Review of Cybertherapy and Telemedicine
Jaime Guixeres, Irene Zaragozá, Mariano Alcañiz, Julio Gomis-Tena, Ausiàs Cebolla