George M. Spyrou

59 papers C 15Journal 39Unranked 4

Year	Rank	Type	Title / Venue / Authors
2026	J	`jnl`	H-SPAR DB: human spaceflight platform for analysis and research - an integrative omics database for space health. Database J. Biol. Databases Curation Marios Tomazou, Marilena M. Bourdakou, Eleni Nicolaidou, Grigoris Georgiou, Kyriaki Savva, Efi Athieniti, Styliana Menelaou, Sotiroula Afxenti, George M. Spyrou
2025	J	`jnl`	IgRENE: integrating gene regulatory networks and drug ontologies towards selected modification of target gene's expression. Briefings Bioinform. George Minadakis, George M. Spyrou
2025	J	`jnl`	Topological influence of immediate-early genes in brain genetic networks and their link to Alzheimer's disease. Comput. Biol. Medicine Margarita Zachariou, Eleni M. Loizidou, George M. Spyrou
2024	J	`jnl`	Combining clinical and molecular data for personalized treatment in acute myeloid leukemia: A machine learning approach. Comput. Methods Programs Biomed. Nestoras Karathanasis, Panayiota L. Papasavva, Anastasis Oulas, George M. Spyrou
2024	J	`jnl`	Ranking of cell clusters in a single-cell RNA-sequencing analysis framework using prior knowledge. PLoS Comput. Biol. Anastasis Oulas, Kyriaki Savva, Nestoras Karathanasis, George M. Spyrou
2023	J	`jnl`	Vir2Drug: a drug repurposing framework based on protein similarities between pathogens. Briefings Bioinform. George Minadakis, Marios Tomazou, Nikolas Dietis, George M. Spyrou
2021	—	`conf`	Computational insights on the molecular mechanisms across breast cancer progression combining gene differential expression and co-expression. BHI Emmanouil K. Ikonomakis, Marilena M. Bourdakou, George Kolios, Michael N. Vrahatis, George M. Spyrou
2021	J	`jnl`	Identification of viral-mediated pathogenic mechanisms in neurodegenerative diseases using network-based approaches. Briefings Bioinform. Anna Onisiforou, George M. Spyrou
2021	J	`jnl`	Multi-omics data integration and network-based analysis drives a multiplex drug repurposing approach to a shortlist of candidate drugs against COVID-19. Briefings Bioinform. Marios Tomazou, Marilena M. Bourdakou, George Minadakis, Margarita Zachariou, Anastasis Oulas, Evangelos Karatzas, Eleni M. Loizidou, Andrea C. Kakouri, Christiana C. Christodoulou, Kyriaki Savva, Maria Zanti, Anna Onisiforou, Sotiroula Afxenti, Jan Richter, Christina G. Christodoulou, Theodoros C. Kyprianou, George Kolios, Nikolas Dietis, George M. Spyrou
2021	J	`jnl`	Performance evaluation of pipelines for mapping, variant calling and interval padding, for the analysis of NGS germline panels. BMC Bioinform. Maria Zanti, Kyriaki Michailidou, Maria Loizidou, Christina Machattou, Panagiota Pirpa, Kyproula Christodoulou, George M. Spyrou, Kyriacos Kyriacou, Andreas Hadjisavvas
2020	J	`jnl`	ChemBioServer 2.0: an advanced web server for filtering, clustering and networking of chemical compounds facilitating both drug discovery and repurposing. Bioinform. Evangelos Karatzas, Juan Eiros Zamora, Emmanouil Athanasiadis, Dimitris Dellis, Zoe Cournia, George M. Spyrou
2020	J	`jnl`	PathWalks: identifying pathway communities using a disease-related map of integrated information. Bioinform. Evangelos Karatzas, Margarita Zachariou, Marilena M. Bourdakou, George Minadakis, Anastasis Oulas, George Kolios, Alex Delis, George M. Spyrou
2019	C	`conf`	Computational Identification of Metabolites for Pathways Related to Huntington's Disease. BIBE Christiana C. Christodoulou, George Minadakis, Christiana Demetriou, Eleni Zamba-Papanicolaou, George M. Spyrou
2019	J	`jnl`	Computational profiling of the gut-brain axis: microflora dysbiosis insights to neurological disorders. Briefings Bioinform. Nikolas Dovrolis, George Kolios, George M. Spyrou, Ioanna Maroulakou
2019	J	`jnl`	Content driven clustering algorithm combining density and distance functions. Pattern Recognit. Emmanouil K. Ikonomakis, George M. Spyrou, Michael N. Vrahatis
2019	C	`conf`	Design and Initial Implementation of a Computer Aided Diagnosis System for PET/CT Solitary Pulmonary Nodule Risk Estimation. BIBE George M. Tzanoukos, Pavlos Kafouris, Alexandros Georgakopoulos, Anastasios Gaitanis, Dimitris Maroulis, Sofia Chatziioannou, George M. Spyrou
2019	C	`conf`	Exploring Fibrotic Disease Networks to Identify Common Molecular Mechanisms with IPF. BIBE Evangelos Karatzas, Alex Delis, George Kolios, George M. Spyrou
2019	C	`conf`	In Silico Assessment of the Structural, Functional and Stability Impact of a Nonsense PRF1 Mutation with Uncertain Clinical Significance; Identified in 2 Unrelated Cypriot Triple-Negative Breast Cancer Patients. BIBE Maria Zanti, Maria Loizidou, Margarita Zachariou, Kyriaki Michailidou, Kyriacos C. Kyriacou, Andreas Hadjisavvas, George M. Spyrou
2019	J	`jnl`	PathwayConnector: finding complementary pathways to enhance functional analysis. Bioinform. George Minadakis, Margarita Zachariou, Anastasis Oulas, George M. Spyrou
2019	J	`jnl`	Revealing Clusters of Connected Pathways Through Multisource Data Integration in Huntington's Disease and Spastic Ataxia. IEEE J. Biomed. Health Informatics Andrea C. Kakouri, Christiana C. Christodoulou, Margarita Zachariou, Anastasis Oulas, George Minadakis, Christiana A. Demetriou, Christina Votsi, Eleni Zamba-Papanicolaou, Kyproula Christodoulou, George M. Spyrou
2019	J	`jnl`	Systems Bioinformatics: increasing precision of computational diagnostics and therapeutics through network-based approaches. Briefings Bioinform. Anastasis Oulas, George Minadakis, Margarita Zachariou, Kleitos Sokratous, Marilena M. Bourdakou, George M. Spyrou
2019	C	`conf`	The Effect of a Spastic Ataxia Associated GBA2 Mutation on Protein-Protein Interactions and Pathways. BIBE Andrea C. Kakouri, Christina Votsi, Marios Tomazou, Kyproula Christodoulou, George M. Spyrou
2017	J	`jnl`	Automatic cumulative sums contour detection of FBP-reconstructed multi-object nuclear medicine images. Comput. Biol. Medicine Nicholas E. Protonotarios, George M. Spyrou, George A. Kastis
2017	J	`jnl`	D-Map: Random Walking on Gene Network Inference Maps Towards differential Avenue Discovery. IEEE ACM Trans. Comput. Biol. Bioinform. Emmanouil Athanasiadis, Marilena M. Bourdakou, George M. Spyrou
2017	J	`jnl`	Informed walks: whispering hints to gene hunters inside networks' jungle. BMC Syst. Biol. Marilena M. Bourdakou, George M. Spyrou
2016	J	`jnl`	Bioinformatics methods in drug repurposing for Alzheimer's disease. Briefings Bioinform. John C. Siavelis, Marilena M. Bourdakou, Emmanouil I. Athanasiadis, George M. Spyrou, Konstantina S. Nikita
2016	J	`jnl`	SPNsim: A database of simulated solitary pulmonary nodule PET/CT images facilitating computer aided diagnosis. J. Biomed. Informatics George M. Tzanoukos, Erast Athanasiadis, Anastasios Gaitanis, Alexandros Georgakopoulos, Achilleas Chatziioannou, Sofia Chatziioannou, George M. Spyrou
2015	J	`jnl`	A CAD$_{\bf x}$ Scheme for Mammography Empowered With Topological Information From Clustered Microcalcifications' Atlases. IEEE J. Biomed. Health Informatics Ioannis Andreadis, George M. Spyrou, Konstantina S. Nikita
2015	J	`jnl`	GeneStoryTeller: a mobile app for quick and comprehensive information retrieval of human genes. Database J. Biol. Databases Curation Stergiani V. Eleftheriou, Marilena M. Bourdakou, Emmanouil I. Athanasiadis, George M. Spyrou
2015	J	`jnl`	ZoomOut: Analyzing Multiple Networks as Single Nodes. IEEE ACM Trans. Comput. Biol. Bioinform. Emmanouil I. Athanasiadis, Marilena M. Bourdakou, George M. Spyrou
2015	J	`jnl`	mAPKL: R/ Bioconductor package for detecting gene exemplars and revealing their characteristics. BMC Bioinform. Argiris Sakellariou, George M. Spyrou
2014	J	`jnl`	A Web-based database of genetic association studies in cutaneous melanoma enhanced with network-driven data exploration tools. Database J. Biol. Databases Curation Emmanouil Athanasiadis, Kyriaki Antonopoulou, Foteini Chatzinasiou, Christina M. Lill, Marilena M. Bourdakou, Argiris Sakellariou, Katerina Kypreou, Irene Stefanaki, Evangelos Evangelou, John P. A. Ioannidis, Lars Bertram, Alexander J. Stratigos, George M. Spyrou
2013	J	`jnl`	BiDaS: a web-based Monte Carlo BioData Simulator based on sequence/feature characteristics. Nucleic Acids Res. Maria D. Paraskevopoulou, Ioannis S. Vlachos, Emmanouil Athanasiadis, George M. Spyrou
2013	C	`conf`	Developing a simulator for multispectral optoacoustic tomography. BIBE Efthymios Maneas, Stratis Tzoumas, Vasilis Ntziachristos, George M. Spyrou
2013	C	`conf`	Generation of clustered microcalcifications' atlases for benign and malignant cases. BIBE Ioannis Andreadis, George M. Spyrou, Panos A. Ligomenides, Konstantina S. Nikita
2013	C	`conf`	Modeling of solitary pulmonary nodules in PET/CT images using Monte Carlo methods. BIBE George M. Tzanoukos, Anastasios Gaitanis, Alexandros Georgakopoulos, Achilleas Chatziioannou, Sofia Chatziioannou, George M. Spyrou
2013	C	`conf`	Performance evaluation of clustering algorithms on microcalcifications as mammography findings. BIBE Emmanouil K. Ikonomakis, George M. Spyrou, Panos A. Ligomenides, Michael N. Vrahatis
2013	C	`conf`	Variations on breast density and subtlety of the findings require different computational intelligence pipelines for the diagnosis of clustered microcalcifications. BIBE Ioannis Andreadis, George M. Spyrou, Panos A. Ligomenides, Konstantina S. Nikita
2012	J	`jnl`	ChemBioServer: a web-based pipeline for filtering, clustering and visualization of chemical compounds used in drug discovery. Bioinform. Emmanouil Athanasiadis, Zoe Cournia, George M. Spyrou
2012	C	`conf`	Clustering microarray data using fuzzy clustering with viewpoints. BIBE Katerina N. Karayianni, George M. Spyrou, Konstantina S. Nikita
2012	J	`jnl`	Combining multiple hypothesis testing and affinity propagation clustering leads to accurate, robust and sample size independent classification on gene expression data. BMC Bioinform. Argiris Sakellariou, Despina Sanoudou, George M. Spyrou
2012	C	`conf`	Enhancing the effectiveness of virtual screening by using the ChemBioServer: Application to the discovery of PI3Kα inhibitors. BIBE Paraskevi Gkeka, Emmanouil Athanasiadis, George M. Spyrou, Zoe Cournia
2012	C	`conf`	e-Prolipsis: A web based risk estimation platform to support and register breast cancer diagnosis in Greece. BIBE Alexandros C. Dimopoulos, John Lakoumentas, Argyro Antaraki, Antonis Frigas, Emmanouil K. Ikonomakis, Marinos Sampson, Anastasios Tagaris, Aikaterini Liakou, Emmanouil Athanasiadis, George M. Spyrou, Panos A. Ligomenides
2011	J	`jnl`	Investigating the Minimum Required Number of Genes for the Classification of Neuromuscular Disease Microarray Data. IEEE Trans. Inf. Technol. Biomed. Argiris Sakellariou, Despina Sanoudou, George M. Spyrou
2011	J	`jnl`	PepServe: a web server for peptide analysis, clustering and visualization. Nucleic Acids Res. Anastasia Alexandridou, Nikolas Dovrolis, George T. Tsangaris, Konstantina S. Nikita, George M. Spyrou
2010	J	`jnl`	A similarity network approach for the analysis and comparison of protein sequence/structure sets. J. Biomed. Informatics Ioannis K. Valavanis, George M. Spyrou, Konstantina S. Nikita
2010	J	`jnl`	Downgrading BIRADS 3 to BIRADS 2 category using a computer-aided microcalcification analysis and risk assessment system for early breast cancer. Comput. Biol. Medicine Georgia Giannakopoulou, George M. Spyrou, Argyro Antaraki, Ioannis Andreadis, Dimitra Koulocheri, Flora Zagouri, Afroditi Nonni, George M. Filippakis, Konstantina S. Nikita, Panos A. Ligomenides, George C. Zografos
2010	J	`jnl`	PET image reconstruction: A stopping rule for the MLEM algorithm based on properties of the updating coefficients. Comput. Medical Imaging Graph. Anastasios Gaitanis, George Kontaxakis, George M. Spyrou, George Panayiotakis, George Tzanakos
2010	J	`jnl`	Studying the properties of the updating coefficients in the OSEM algorithm for iterative image reconstruction in PET. Comput. Methods Programs Biomed. Anastasios Gaitanis, George Kontaxakis, George M. Spyrou, George Panayiotakis, George Tzanakos
2009	—	`conf`	Design of a 'Smart' Patient Record System for Mammography Patients. MIE Antonis Frigas, George M. Spyrou, Argyro Antaraki, Elisabeth Patiraki, Konstantinos Koufopoulos, John Mantas, Panos A. Ligomenides
2009	J	`jnl`	UniMaP: finding unique mass and peptide signatures in the human proteome. Bioinform. Anastasia Alexandridou, George T. Tsangaris, Konstantinos N. Vougas, Konstantina S. Nikita, George M. Spyrou
2008	C	`conf`	A high throughput approach to keep alive a web-based database system for multiple search among published bioinformatics tools and databases. BIBE Vassilis Atlamazoglou, Trias Thireou, Anastasia Alexandridou, George M. Spyrou
2008	J	`jnl`	Peptide Finder: mapping measured molecular masses to peptides and proteins. Bioinform. Anastasia Alexandridou, George T. Tsangaris, Konstantinos N. Vougas, Konstantina S. Nikita, George M. Spyrou
2008	C	`conf`	Protein similarity networks and Genetic Algorithm driven feature selection for fold recognition. BIBE Ioannis K. Valavanis, George M. Spyrou, Konstantina S. Nikita
2007	J	`jnl`	A Survey of the Availability of Primary Bioinformatics Web Resources. Genom. Proteom. Bioinform. Trias Thireou, George M. Spyrou, Vassilis Atlamazoglou
2006	J	`jnl`	"Hippocrates-mst": a prototype for computer-aided microcalcification analysis and risk assessment for breast cancer. Medical Biol. Eng. Comput. George M. Spyrou, Smaragda Kapsimalakou, Antonis Frigas, Konstantinos Koufopoulos, Stamatios Vassilaros, Panos A. Ligomenides
2006	—	`conf`	Evaluation of a Breast Cancer Computer Aided Diagnosis System. MIE Antonis Frigas, Smaragda Kapsimalakou, George M. Spyrou, Konstantinos Koufopoulos, Stamatios Vassilaros, Aikaterini Chatzimichael, John Mantas, Panos A. Ligomenides
2006	—	`conf`	Study on Preprocessing and Classifying Mass Spectral Raw Data Concerning Human Normal and Disease Cases. ISBMDA Xenofon E. Floros, George M. Spyrou, Konstantinos N. Vougas, George T. Tsangaris, Konstantina S. Nikita
2001	—	`—`	Development of a simulation algorithm for mammographic imaging based on Monte Carlo methods George M. Spyrou