Douglas A. Lauffenburger

24 papers C 2Journal 20Unranked 2
YearRankTypeTitle / Venue / Authors
2024 J jnl
New biological solutions to the many problems of our time.
Autom.
Douglas A. Lauffenburger, Heinz Koeppl
2019 J jnl
Computational translation of genomic responses from experimental model systems to humans.
PLoS Comput. Biol.
Douglas K. Brubaker, Elizabeth A. Proctor, Kevin M. Haigis, Douglas A. Lauffenburger
2018 J jnl
Exploiting glycan topography for computational design of Env glycoprotein antigenicity.
PLoS Comput. Biol.
Wen-Han Yu, Peng Zhao, Monia Draghi, Claudia Arevalo, Christina B. Karsten, Todd J. Suscovich, Bronwyn Gunn, Hendrik Streeck, Abraham L. Brass, Michael Tiemeyer, Michael S. Seaman, John R. Mascola, Lance Wells, Douglas A. Lauffenburger, Galit Alter
2013 C conf
Identification of signaling pathways related to drug efficacy in hepatocellular carcinoma via integration of phosphoproteomic, genomic and clinical data.
BIBE
Ioannis N. Melas, Douglas A. Lauffenburger, Leonidas G. Alexopoulos
2013 J jnl
Linking Proteomic and Transcriptional Data through the Interactome and Epigenome Reveals a Map of Oncogene-induced Signaling.
PLoS Comput. Biol.
Shao-Shan Carol Huang, David C. Clarke, Sara J. C. Gosline, Adam Labadorf, Candace R. Chouinard, William Gordon, Douglas A. Lauffenburger, Ernest Fraenkel
2012 J jnl
CellNOptR: a flexible toolkit to train protein signaling networks to data using multiple logic formalisms.
BMC Syst. Biol.
Camille Terfve, Thomas Cokelaer, David Henriques, Aidan MacNamara, Emanuel J. V. Gonçalves, Melody K. Morris, Martijn P. van Iersel, Douglas A. Lauffenburger, Julio Saez-Rodriguez
2012 J jnl
Creating and analyzing pathway and protein interaction compendia for modelling signal transduction networks.
BMC Syst. Biol.
Daniel C. Kirouac, Julio Saez-Rodriguez, Jennifer Swantek, John M. Burke, Douglas A. Lauffenburger, Peter K. Sorger
2012 J jnl
Modular Design of Artificial Tissue Homeostasis: Robust Control through Synthetic Cellular Heterogeneity.
PLoS Comput. Biol.
Miles Miller, Marc Hafner, Eduardo D. Sontag, Noah Davidsohn, Sairam Subramanian, Priscilla E. M. Purnick, Douglas A. Lauffenburger, Ron Weiss
2011 J jnl
A Dynamical Systems Model for Combinatorial Cancer Therapy Enhances Oncolytic Adenovirus Efficacy by MEK-Inhibition.
PLoS Comput. Biol.
Neda Bagheri, Marisa Shiina, Douglas A. Lauffenburger, W. Michael Korn
2011 J jnl
MCAM: Multiple Clustering Analysis Methodology for Deriving Hypotheses and Insights from High-Throughput Proteomic Datasets.
PLoS Comput. Biol.
Kristen M. Naegle, Roy E. Welsch, Michael B. Yaffe, Forest M. White, Douglas A. Lauffenburger
2011 J jnl
Training Signaling Pathway Maps to Biochemical Data with Constrained Fuzzy Logic: Quantitative Analysis of Liver Cell Responses to Inflammatory Stimuli.
PLoS Comput. Biol.
Melody K. Morris, Julio Saez-Rodriguez, David C. Clarke, Peter K. Sorger, Douglas A. Lauffenburger
2009 J jnl
Fuzzy Logic Analysis of Kinase Pathway Crosstalk in TNF/EGF/Insulin-Induced Signaling.
PLoS Comput. Biol.
Bree B. Aldridge, Julio Saez-Rodriguez, Jeremy Muhlich, Peter K. Sorger, Douglas A. Lauffenburger
2009 J jnl
Learning Signaling Network Structures with Sparsely Distributed Data.
J. Comput. Biol.
Karen Sachs, Solomon Itani, Jennifer Carlisle, Garry P. Nolan, Dana Pe'er, Douglas A. Lauffenburger
2009 J jnl
Transforming Boolean models to continuous models: methodology and application to T-cell receptor signaling.
BMC Syst. Biol.
Dominik M. Wittmann, Jan Krumsiek, Julio Saez-Rodriguez, Douglas A. Lauffenburger, Steffen Klamt, Fabian J. Theis
2008 J jnl
Flexible informatics for linking experimental data to mathematical models via
Bioinform.
Julio Saez-Rodriguez, Arthur Goldsipe, Jeremy Muhlich, Leonidas G. Alexopoulos, Bjorn Millard, Douglas A. Lauffenburger, Peter K. Sorger
2008 C conf
Modeling pro-death signaling pathways in cancer hepatocytes using multi-combinatorial treatments of inhibitors and stimuli.
BIBE
Leonidas G. Alexopoulos, Douglas A. Lauffenburger, Peter K. Sorger
2007 J jnl
Decision tree modeling predicts effects of inhibiting contractility signaling on cell motility.
BMC Syst. Biol.
Sourabh Kharait, Sampsa Hautaniemi, Shan Wu, Akihiro Iwabu, Douglas A. Lauffenburger, Alan Wells
2007 J jnl
Modeling HER2 Effects on Cell Behavior from Mass Spectrometry Phosphotyrosine Data.
PLoS Comput. Biol.
Neil Kumar, Alejandro Wolf-Yadlin, Forest M. White, Douglas A. Lauffenburger
2005 J jnl
Bayesian analysis of signaling networks governing embryonic stem cell fate decisions.
Bioinform.
Peter J. Woolf, Wendy Prudhomme, Laurence Daheron, George Q. Daley, Douglas A. Lauffenburger
2005 J jnl
Modeling of signal-response cascades using decision tree analysis.
Bioinform.
Sampsa Hautaniemi, Sourabh Kharait, Akihiro Iwabu, Alan Wells, Douglas A. Lauffenburger
2004 — conf
Analysis of Signaling Pathways in Human T-Cells Using Bayesian Network Modeling of Single Cell Data.
CSB
Karen Sachs, Omar D. Perez, Dana Pe'er, Garry P. Nolan, David K. Gifford, Tommi S. Jaakkola, Douglas A. Lauffenburger
2004 J jnl
Cue-Signal-Response Analysis of TNF-Induced Apoptosis by Partial Least Squares Regression of Dynamic Multivariate Data.
J. Comput. Biol.
Kevin A. Janes, Jason R. Kelly, Suzanne Gaudet, John G. Albeck, Peter K. Sorger, Douglas A. Lauffenburger
2003 — conf
Modeling cellular signal processing using interacting Markov chains.
ICASSP (6)
Maya R. Said, Alan V. Oppenheim, Douglas A. Lauffenburger
1994 J jnl
Probability of Autocrine Ligand Capture by Cell-Surface Receptors: Implications for Ligand Secretion Measurements.
J. Comput. Biol.
Kimberly E. Forsten, Douglas A. Lauffenburger