Denise E. Kirschner

16 papers Journal 15Unranked 1
YearRankTypeTitle / Venue / Authors
2025 J jnl
Distinguishing multiple roles of T cell and macrophage involvement in determining lymph node fates during Mycobacterium tuberculosis infection.
PLoS Comput. Biol.
Kathryn C. Krupinsky, Christian T. Michael, Pariksheet Nanda, Joshua T. Mattila, Denise E. Kirschner
2023 J jnl
Calibration methods to fit parameters within complex biological models.
Frontiers Appl. Math. Stat.
Pariksheet Nanda, Denise E. Kirschner
2023 J jnl
Optimizing tuberculosis treatment efficacy: Comparing the standard regimen with Moxifloxacin-containing regimens.
PLoS Comput. Biol.
Maral Budak, Joseph M. Cicchese, Pauline Maiello, H. Jacob Borish, Alexander G. White, Harris B. Chishti, Jaime Tomko, L. James Frye, Daniel Fillmore, Kara Kracinovsky, Jennifer Sakal, Charles A. Scanga, Philana Ling Lin, Véronique Dartois, Jennifer J. Linderman, JoAnne L. Flynn, Denise E. Kirschner
2020 J jnl
A computational model tracks whole-lung Mycobacterium tuberculosis infection and predicts factors that inhibit dissemination.
PLoS Comput. Biol.
Timothy Wessler, Louis R. Joslyn, H. Jacob Borish, Hannah P. Gideon, JoAnne L. Flynn, Denise E. Kirschner, Jennifer J. Linderman
2020 J jnl
Systems biology predicts that fibrosis in tuberculous granulomas may arise through macrophage-to-myofibroblast transformation.
PLoS Comput. Biol.
Stephanie Evans, J. Russell Butler, Joshua T. Mattila, Denise E. Kirschner
2018 J jnl
The Role of Dimensionality in Understanding Granuloma Formation.
Comput.
Simeone Marino, Caitlin Hult, Paul Wolberg, Jennifer J. Linderman, Denise E. Kirschner
2017 J jnl
Comparing efficacies of moxifloxacin, levofloxacin and gatifloxacin in tuberculosis granulomas using a multi-scale systems pharmacology approach.
PLoS Comput. Biol.
Elsje Pienaar, Jansy Sarathy, Brendan Prideaux, Jillian Dietzold, Véronique Dartois, Denise E. Kirschner, Jennifer J. Linderman
2016 J jnl
A Multi-Compartment Hybrid Computational Model Predicts Key Roles for Dendritic Cells in Tuberculosis Infection.
Comput.
Simeone Marino, Denise E. Kirschner
2016 J jnl
Computational and Empirical Studies Predict Mycobacterium tuberculosis-Specific T Cells as a Biomarker for Infection Outcome.
PLoS Comput. Biol.
Simeone Marino, Hannah P. Gideon, Chang Gong, Shawn Mankad, John T. McCrone, Philana Ling Lin, Jennifer J. Linderman, JoAnne L. Flynn, Denise E. Kirschner
2010 J jnl
Identification of Key Processes that Control Tumor Necrosis Factor Availability in a Tuberculosis Granuloma.
PLoS Comput. Biol.
Mohammad Fallahi-Sichani, Matthew A. Schaller, Denise E. Kirschner, Steven L. Kunkel, Jennifer J. Linderman
2009 — conf
Data-parallel algorithms for agent-based model simulation of tuberculosis on graphics processing units.
SpringSim
Roshan M. D'Souza, Mikola Lysenko, Simeone Marino, Denise E. Kirschner
2007 J jnl
Differences in Reactivation of Tuberculosis Induced from Anti-TNF Treatments Are Based on Bioavailability in Granulomatous Tissue.
PLoS Comput. Biol.
Simeone Marino, Dhruv Sud, Hillarie Plessner, Philana Ling Lin, John Chan, JoAnne L. Flynn, Denise E. Kirschner
2007 J jnl
Identifying DNA splice sites using hypernetworks with artificial molecular evolution.
Biosyst.
Jose L. Segovia-Juarez, Silvano Colombano, Denise E. Kirschner
2006 J jnl
Peptide length-based prediction of peptide-MHC class II binding.
Bioinform.
Stewart T. Chang, Debashis Ghosh, Denise E. Kirschner, Jennifer J. Linderman
2005 J jnl
Understanding the Immune Response in Tuberculosis Using Different Mathematical Models and Biological Scales.
Multiscale Model. Simul.
David Gammack, Suman Ganguli, Simeone Marino, Jose L. Segovia-Juarez, Denise E. Kirschner
1996 J jnl
A Diffusion Model for AIDS in a Closed, Heterosexual Population: Examining Rates of Infection.
SIAM J. Appl. Math.
Denise E. Kirschner