David N. Cooper

23 papers Journal 22Unranked 1
YearRankTypeTitle / Venue / Authors
2023 J jnl
Inferring the genetic relationship between brain imaging-derived phenotypes and risk of complex diseases by Mendelian randomization and genome-wide colocalization.
NeuroImage
Siying Lin, Haoyang Zhang, Mengling Qi, David N. Cooper, Yuedong Yang, Yuanhao Yang, Huiying Zhao
2021 J jnl
MutationTaster2021.
Nucleic Acids Res.
Robin Steinhaus, Sebastian Proft, Markus Schuelke, David N. Cooper, Jana Marie Schwarz, Dominik Seelow
2019 J jnl
Pathogenicity and functional impact of non-frameshifting insertion/deletion variation in the human genome.
PLoS Comput. Biol.
Kymberleigh A. Pagel, Danny Antaki, Aojie Lian, Matthew E. Mort, David N. Cooper, Jonathan Sebat, Lilia M. Iakoucheva, Sean D. Mooney, Predrag Radivojac
2019 J jnl
RegulationSpotter: annotation and interpretation of extratranscriptic DNA variants.
Nucleic Acids Res.
Jana Marie Schwarz, Daniela Hombach, Sebastian Köhler, David N. Cooper, Markus Schuelke, Dominik Seelow
2019 J jnl
SeqTailor: a user-friendly webserver for the extraction of DNA or protein sequences from next-generation sequencing data.
Nucleic Acids Res.
Peng Zhang, Bertrand Boisson, Peter D. Stenson, David N. Cooper, Jean-Laurent Casanova, Laurent Abel, Yuval Itan
2018 J jnl
FATHMM-XF: accurate prediction of pathogenic point mutations via extended features.
Bioinform.
Mark F. Rogers, Hashem A. Shihab, Matthew E. Mort, David N. Cooper, Tom R. Gaunt, Colin Campbell
2018 J jnl
Mutational signatures and mutable motifs in cancer genomes.
Briefings Bioinform.
Igor B. Rogozin, Youri I. Pavlov, Alexander Goncearenco, Subhajyoti De, Artem G. Lada, Eugenia Poliakov, Anna R. Panchenko, David N. Cooper
2017 J jnl
An integrative approach to predicting the functional effects of small indels in non-coding regions of the human genome.
BMC Bioinform.
Michael Ferlaino, Mark F. Rogers, Hashem A. Shihab, Matthew E. Mort, David N. Cooper, Tom R. Gaunt, Colin Campbell
2017 J jnl
When loss-of-function is loss of function: assessing mutational signatures and impact of loss-of-function genetic variants.
Bioinform.
Kymberleigh A. Pagel, Vikas Pejaver, Guan Ning Lin, Hyun-Jun Nam, Matthew E. Mort, David N. Cooper, Jonathan Sebat, Lilia M. Iakoucheva, Sean D. Mooney, Predrag Radivojac
2016 J jnl
Mining clinical attributes of genomic variants through assisted literature curation in Egas.
Database J. Biol. Databases Curation
Sérgio Matos, David Campos, Renato P. Pinho, Raquel M. Silva, Matthew E. Mort, David N. Cooper, José Luís Oliveira
2016 J jnl
The Loss and Gain of Functional Amino Acid Residues Is a Common Mechanism Causing Human Inherited Disease.
PLoS Comput. Biol.
Jose Lugo-Martinez, Vikas Pejaver, Kymberleigh A. Pagel, Shantanu Jain, Matthew E. Mort, David N. Cooper, Sean D. Mooney, Predrag Radivojac
2015 J jnl
An integrative approach to predicting the functional effects of non-coding and coding sequence variation.
Bioinform.
Hashem A. Shihab, Mark F. Rogers, Julian Gough, Matthew E. Mort, David N. Cooper, Ian N. M. Day, Tom R. Gaunt, Colin Campbell
2015 J jnl
DDIG-in: detecting disease-causing genetic variations due to frameshifting indels and nonsense mutations employing sequence and structural properties at nucleotide and protein levels.
Bioinform.
Lukas Folkman, Yuedong Yang, Zhixiu Li, Bela Stantic, Abdul Sattar, Matthew E. Mort, David N. Cooper, Yunlong Liu, Yaoqi Zhou
2015 — conf
Sequential data selection for predicting the pathogenic effects of sequence variation.
BIBM
Mark F. Rogers, Colin Campbell, Hashem A. Shihab, Tom R. Gaunt, Matthew E. Mort, David N. Cooper
2014 J jnl
A Probabilistic Model to Predict Clinical Phenotypic Traits from Genome Sequencing.
PLoS Comput. Biol.
Yun-Ching Chen, Christopher Douville, Cheng Wang, Noushin Niknafs, Grace H. T. Yeo, Violeta Beleva Guthrie, Hannah Carter, Peter D. Stenson, David N. Cooper, Biao Li, Sean D. Mooney, Rachel Karchin
2013 J jnl
CRAVAT: cancer-related analysis of variants toolkit.
Bioinform.
Christopher Douville, Hannah Carter, Rick Kim, Noushin Niknafs, Mark Diekhans, Peter D. Stenson, David N. Cooper, Michael C. Ryan, Rachel Karchin
2013 J jnl
Predicting the functional consequences of cancer-associated amino acid substitutions.
Bioinform.
Hashem A. Shihab, Julian Gough, David N. Cooper, Ian N. M. Day, Tom R. Gaunt
2012 J jnl
regSNPs: a strategy for prioritizing regulatory single nucleotide substitutions.
Bioinform.
Mingxiang Teng, Shoji Ichikawa, Leah R. Padgett, Yadong Wang, Matthew E. Mort, David N. Cooper, Daniel L. Koller, Tatiana Foroud, Howard J. Edenberg, Michael J. Econs, Yunlong Liu
2010 J jnl
Structure-based kernels for the prediction of catalytic residues and their involvement in human inherited disease.
Bioinform.
Fuxiao Xin, Steven A. Myers, Yong Fuga Li, David N. Cooper, Sean D. Mooney, Predrag Radivojac
2010 J jnl
Structure-based kernels for the prediction of catalytic residues and their involvement in human inherited disease.
BMC Bioinform.
Fuxiao Xin, Steven A. Myers, Yong Fuga Li, David N. Cooper, Sean D. Mooney, Predrag Radivojac
2009 J jnl
Automated inference of molecular mechanisms of disease from amino acid substitutions.
Bioinform.
Biao Li, Vidhya G. Krishnan, Matthew E. Mort, Fuxiao Xin, Kishore K. Kamati, David N. Cooper, Sean D. Mooney, Predrag Radivojac
2006 J jnl
In Silico Discrimination of Single Nucleotide Polymorphisms and Pathological Mutations in Human Gene Promoter Regions by Means of Local DNA Sequence Context and Regularity.
Silico Biol.
Imtiaz A. Khan, Matthew E. Mort, Paul R. Buckland, Michael C. O'Donovan, David N. Cooper, Nadia A. Chuzhanova
1998 J jnl
The human gene mutation database.
Nucleic Acids Res.
David N. Cooper, Edward V. Ball, Michael Krawczak