Aleksander S. Popel

25 papers Misc 1Journal 22Unranked 2
YearRankTypeTitle / Venue / Authors
2025 J jnl
Bi-level graph learning unveils prognosis-relevant tumor microenvironment patterns in breast multiplexed digital pathology.
Patterns
Zhenzhen Wang, Cesar A. Santa-Maria, Aleksander S. Popel, Jeremias Sulam
2025 — conf
Concept Bottleneck Model with Zero Performance Loss.
CPAL
Zhenzhen Wang, Aleksander S. Popel, Jeremias Sulam
2024 J jnl
Computational methods and biomarker discovery strategies for spatial proteomics: a review in immuno-oncology.
Briefings Bioinform.
Haoyang Mi, Shamilene Sivagnanam, Won Jin Ho, Shuming Zhang, Daniel R. Bergman, Atul Deshpande, Alexander S. Baras, Elizabeth M. Jaffee, Lisa M. Coussens, Elana J. Fertig, Aleksander S. Popel
2024 J jnl
From virtual patients to digital twins in immuno-oncology: lessons learned from mechanistic quantitative systems pharmacology modeling.
npj Digit. Medicine
Hanwen Wang, Theinmozhi Arulraj, Alberto Ippolito, Aleksander S. Popel
2024 J jnl
Leveraging multi-omics data to empower quantitative systems pharmacology in immuno-oncology.
Briefings Bioinform.
Theinmozhi Arulraj, Hanwen Wang, Alberto Ippolito, Shuming Zhang, Elana J. Fertig, Aleksander S. Popel
2022 J jnl
Label Cleaning Multiple Instance Learning: Refining Coarse Annotations on Single Whole-Slide Images.
IEEE Trans. Medical Imaging
Zhenzhen Wang, Carla Saoud, Sintawat Wangsiricharoen, Aaron W. James, Aleksander S. Popel, Jeremias Sulam
2022 J jnl
Simulations of tumor growth and response to immunotherapy by coupling a spatial agent-based model with a whole-patient quantitative systems pharmacology model.
PLoS Comput. Biol.
Alvaro Ruiz-Martinez, Chang Gong, Hanwen Wang, Richard J. Sové, Haoyang Mi, Holly Kimko, Aleksander S. Popel
2021 J jnl
Label Cleaning Multiple Instance Learning: Refining Coarse Annotations on Single Whole-Slide Images.
CoRR
Zhenzhen Wang, Aleksander S. Popel, Jeremias Sulam
2019 J jnl
A mechanistic integrative computational model of macrophage polarization: Implications in human pathophysiology.
PLoS Comput. Biol.
Chen Zhao, Adam C. Mirando, Richard J. Sové, Thalyta X. Medeiros, Brian H. Annex, Aleksander S. Popel
2017 J jnl
An agent-based model of triple-negative breast cancer: the interplay between chemokine receptor CCR5 expression, cancer stem cells, and hypoxia.
BMC Syst. Biol.
Kerri-Ann Norton, Travis Wallace, Niranjan B. Pandey, Aleksander S. Popel
2017 J jnl
Computational investigation of sphingosine kinase 1 (SphK1) and calcium dependent ERK1/2 activation downstream of VEGFR2 in endothelial cells.
PLoS Comput. Biol.
Hojjat Bazzazi, Aleksander S. Popel
2017 J jnl
Transcriptional and Post-Transcriptional Regulation of Thrombospondin-1 Expression: A Computational Model.
PLoS Comput. Biol.
Chen Zhao, Jeffrey S. Isenberg, Aleksander S. Popel
2015 — conf
A 3D Fractal-Based Approach towards Understanding Changes in the Infarcted Heart Microvasculature.
MICCAI (3)
Polyxeni Gkontra, Magdalena M. Zak, Kerri-Ann Norton, Andrés Santos, Aleksander S. Popel, Alicia G. Arroyo
2015 J jnl
Computational Model of MicroRNA Control of HIF-VEGF Pathway: Insights into the Pathophysiology of Ischemic Vascular Disease and Cancer.
PLoS Comput. Biol.
Chen Zhao, Aleksander S. Popel
2011 J jnl
Formation of VEGF isoform-specific spatial distributions governing angiogenesis: computational analysis.
BMC Syst. Biol.
Prakash Vempati, Aleksander S. Popel, Feilim Mac Gabhann
2011 J jnl
Pharmacokinetics and pharmacodynamics of VEGF-neutralizing antibodies.
BMC Syst. Biol.
Stacey D. Finley, Marianne O. Engel-Stefanini, Princess I. Imoukhuede, Aleksander S. Popel
2009 J jnl
Elongation, proliferation & migration differentiate endothelial cell phenotypes and determine capillary sprouting.
BMC Syst. Biol.
Amina A. Qutub, Aleksander S. Popel
2009 Misc conf
Integration of Angiogenesis Modules at Multiple Scales: From Molecular to Tissue.
Pacific Symposium on Biocomputing
Amina A. Qutub, Gang Liu, Prakash Vempati, Aleksander S. Popel
2009 J jnl
The Presence of VEGF Receptors on the Luminal Surface of Endothelial Cells Affects VEGF Distribution and VEGF Signaling.
PLoS Comput. Biol.
Marianne O. Stefanini, Florence T. H. Wu, Feilim Mac Gabhann, Aleksander S. Popel
2008 J jnl
A compartment model of VEGF distribution in blood, healthy and diseased tissues.
BMC Syst. Biol.
Marianne O. Stefanini, Florence T. H. Wu, Feilim Mac Gabhann, Aleksander S. Popel
2006 J jnl
Computational Model of Vascular Endothelial Growth Factor Spatial Distribution in Muscle and Pro-Angiogenic Cell Therapy.
PLoS Comput. Biol.
Feilim Mac Gabhann, James W. Ji, Aleksander S. Popel
2006 J jnl
Targeting Neuropilin-1 to Inhibit VEGF Signaling in Cancer: Comparison of Therapeutic Approaches.
PLoS Comput. Biol.
Feilim Mac Gabhann, Aleksander S. Popel
1999 J jnl
Canine sternal force-displacement relationship during cardiopulmonary resuscitation.
IEEE Trans. Biomed. Eng.
Kreg G. Gruben, Henry R. Halperin, Aleksander S. Popel, Joshua E. Tsitlik
1996 J jnl
Potential distribution for a spheroidal cell having a conductive membrane in an electric field.
IEEE Trans. Biomed. Eng.
Rocco A. Jerry, Aleksander S. Popel, William E. Brownell
1990 J jnl
Identification of dynamic mechanical parameters of the human chest during manual cadiopulmonary resuscitation.
IEEE Trans. Biomed. Eng.
Isaac N. Bankman, Kreg G. Gruben, Henry R. Halperin, Aleksander S. Popel, Alan D. Guerci, Joshua E. Tsitlik