Aik Choon Tan

27 papers B 1C 2Journal 23Unranked 1
YearRankTypeTitle / Venue / Authors
2024 J jnl
An Epigenomic fingerprint of human cancers by landscape interrogation of super enhancers at the constituent level.
PLoS Comput. Biol.
Xiang Liu, Nancy Gillis, Chang Jiang, Anthony McCofie, Timothy I. Shaw, Aik Choon Tan, Bo Zhao, Lixin Wan, Derek R. Duckett, Mingxiang Teng
2023 J jnl
Editorial: AI and data science in drug development and public health: Highlights from the MCBIOS 2022 conference.
Frontiers Big Data
Ramin Homayouni, Prashanti Manda, Aik Choon Tan, Zhaohui S. Qin
2023 J jnl
NuKit: A deep learning platform for fast nucleus segmentation of histopathological images.
J. Bioinform. Comput. Biol.
Ching-Nung Lin, Christine H. Chung, Aik Choon Tan
2023 J jnl
PATH-SURVEYOR: pathway level survival enquiry for immuno-oncology and drug repurposing.
BMC Bioinform.
Alyssa N. Obermayer, Darwin Chang, Gabrielle Nobles, Mingxiang Teng, Aik Choon Tan, Xuefeng Wang, Y. Ann Chen, Steven Eschrich, Paulo C. Rodriguez, G. Daniel Grass, Soheil Meshinchi, Ahmad Tarhini, Dung-Tsa Chen, Timothy I. Shaw
2021 J jnl
Crowdsourced identification of multi-target kinase inhibitors for RET- and TAU- based disease: The Multi-Targeting Drug DREAM Challenge.
PLoS Comput. Biol.
Zhaoping Xiong, Minji Jeon, Robert J. Allaway, Jaewoo Kang, Donghyeon Park, Jinhyuk Lee, Hwisang Jeon, Miyoung Ko, Hualiang Jiang, Mingyue Zheng, Aik Choon Tan, Xindi Guo, Multi-Targeting Drug DREAM Challenge Community, Kristen K. Dang, Alexander Tropsha, Chana Hecht, Tirtha K. Das, Heather A. Carlson, Ruben Abagyan, Justin Guinney, Avner Schlessinger, Ross L. Cagan
2021 J jnl
Deep Learning of Histopathology Images at the Single Cell Level.
Frontiers Artif. Intell.
Kyubum Lee, John H. Lockhart, Mengyu Xie, Ritu Chaudhary, Robbert J. C. Slebos, Elsa R. Flores, Christine H. Chung, Aik Choon Tan
2021 J jnl
TIMEx: tumor-immune microenvironment deconvolution web-portal for bulk transcriptomics using pan-cancer scRNA-seq signatures.
Bioinform.
Mengyu Xie, Kyubum Lee, John H. Lockhart, Scott D. Cukras, Rodrigo Carvajal, Amer A. Beg, Elsa R. Flores, Mingxiang Teng, Christine H. Chung, Aik Choon Tan
2019 J jnl
Exploring the molecular mechanisms of Traditional Chinese Medicine components using gene expression signatures and connectivity map.
Comput. Methods Programs Biomed.
Minjae Yoo, Jimin Shin, Hyunmin Kim, Jihye Kim, Jaewoo Kang, Aik Choon Tan
2019 J jnl
ReSimNet: drug response similarity prediction using Siamese neural networks.
Bioinform.
Minji Jeon, Donghyeon Park, Jinhyuk Lee, Hwisang Jeon, Miyoung Ko, Sunkyu Kim, Yonghwa Choi, Aik Choon Tan, Jaewoo Kang
2018 J jnl
Deep learning of mutation-gene-drug relations from the literature.
BMC Bioinform.
Kyubum Lee, Byounggun Kim, Yonghwa Choi, Sunkyu Kim, Won-Ho Shin, Sunwon Lee, Sungjoon Park, Seongsoon Kim, Aik Choon Tan, Jaewoo Kang
2018 J jnl
GSEA-InContext: identifying novel and common patterns in expression experiments.
Bioinform.
Rani K. Powers, Andrew Goodspeed, Harrison Pielke-Lombardo, Aik Choon Tan, James C. Costello
2018 J jnl
PAGER 2.0: an update to the pathway, annotated-list and gene-signature electronic repository for Human Network Biology.
Nucleic Acids Res.
Zongliang Yue, Qi Zheng, Michael T. Neylon, Minjae Yoo, Jimin Shin, Zhiying Zhao, Aik Choon Tan, Jake Y. Chen
2016 J jnl
BRONCO: Biomedical entity Relation ONcology COrpus for extracting gene-variant-disease-drug relations.
Database J. Biol. Databases Curation
Kyubum Lee, Sunwon Lee, Sungjoon Park, Sunkyu Kim, Suhkyung Kim, Kwanghun Choi, Aik Choon Tan, Jaewoo Kang
2016 J jnl
HiPub: translating PubMed and PMC texts to networks for knowledge discovery.
Bioinform.
Kyubum Lee, Won-Ho Shin, Byounggun Kim, Sunwon Lee, Yonghwa Choi, Sunkyu Kim, Minji Jeon, Aik Choon Tan, Jaewoo Kang
2016 J jnl
IMPACT: a whole-exome sequencing analysis pipeline for integrating molecular profiles with actionable therapeutics in clinical samples.
J. Am. Medical Informatics Assoc.
Jennifer Hintzsche, Jihye Kim, Vinod Kumar Yadav, Carol Amato, Steven E. Robinson, Eric Seelenfreund, Yiqun Shellman, Joshua Wisell, Allison Applegate, Martin McCarter, Neil Box, John Tentler, Subhajyoti De, William A. Robinson, Aik Choon Tan
2015 J jnl
DSigDB: drug signatures database for gene set analysis.
Bioinform.
Minjae Yoo, Jimin Shin, Jihye Kim, Karen A. Ryall, Kyubum Lee, Sunwon Lee, Minji Jeon, Jaewoo Kang, Aik Choon Tan
2015 J jnl
Identifying kinase dependency in cancer cells by integrating high-throughput drug screening and kinase inhibition data.
Bioinform.
Karen A. Ryall, Jimin Shin, Minjae Yoo, Trista K. Hinz, Jihye Kim, Jaewoo Kang, Lynn E. Heasley, Aik Choon Tan
2015 J jnl
Systems biology approaches for advancing the discovery of effective drug combinations.
J. Cheminformatics
Karen A. Ryall, Aik Choon Tan
2014 J jnl
BEReX: Biomedical Entity-Relationship eXplorer.
Bioinform.
Minji Jeon, Sunwon Lee, Kyubum Lee, Aik Choon Tan, Jaewoo Kang
2014 J jnl
Bioinformatics-driven discovery of rational combination for overcoming EGFR-mutant lung cancer resistance to EGFR therapy.
Bioinform.
Jihye Kim, Vihas T. Vasu, Rangnath Mishra, Katherine R. Singleton, Minjae Yoo, Sonia M. Leach, Eveline Farias-Hesson, Robert J. Mason, Jaewoo Kang, Preveen Ramamoorthy, Jeffrey A. Kern, Lynn E. Heasley, James H. Finigan, Aik Choon Tan
2008 J jnl
Merging microarray data from separate breast cancer studies provides a robust prognostic test.
BMC Bioinform.
Lei Xu, Aik Choon Tan, Raimond L. Winslow, Donald Geman
2008 C conf
Microarray Classification from Several Two-Gene Expression Comparisons.
ICMLA
Donald Geman, Bahman Afsari, Aik Choon Tan, Daniel Q. Naiman
2005 J jnl
Robust prostate cancer marker genes emerge from direct integration of inter-study microarray data.
Bioinform.
Lei Xu, Aik Choon Tan, Daniel Q. Naiman, Donald Geman, Raimond L. Winslow
2005 J jnl
Simple decision rules for classifying human cancers from gene expression profiles.
Bioinform.
Aik Choon Tan, Daniel Q. Naiman, Lei Xu, Raimond L. Winslow, Donald Geman
2004 C conf
An Assessment of Feature Relevance in Predicting Protein Function from Sequence.
IDEAL
Ali Al-Shahib, Chao He, Aik Choon Tan, Mark A. Girolami, David R. Gilbert
2003 B conf
An Empirical Comparison of Supervised Machine Learning Techniques in Bioinformatics.
APBC
Aik Choon Tan, David R. Gilbert
2003 — conf
Integrative machine learning approach for multi-class SCOP protein fold classification.
German Conference on Bioinformatics
Aik Choon Tan, David R. Gilbert, Yves Deville